::Science::
HIV-1 RNA
SELEX stategies
RNA evolution
The use of bioinformatics methods to predict RNA structure have
lead me into an interest in RNA evolution. The basic evolution
by conservative base substitutions, but studying RNA changes on
a larger scale has been observed for primate lentiviruses, where
the changes makes sense in the light of the palindrome mentioned
above (ref). A further study of developing an RNA editor we studies
the Rfam database (ref).
Biophysical methods
I have been participating in projects to use Atomic Force Microscopy
(AFM) to study RNA structure. Lately I have been using the method
Small-Angle X-ray Scattering (SAXS).